Using this toothpaste is easy. First, put a small amount of the toothpaste on a dog - friendly toothbrush. Gently lift your dog's lips and brush their teeth in circular motions. Make sure to cover all surfaces of the teeth. Do this regularly, preferably daily, for the best results. Remember, only use toothpaste made for dogs as human toothpaste can be harmful. Store the toothpaste in a cool, dry place to keep it fresh. If your dog shows any signs of discomfort during brushing, stop and consult your vet.